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Year : 2020  |  Volume : 30  |  Issue : 3  |  Page : 354-361
Holography applications toward medical field: An overview

1 Department of Mechanical Engineering, Jamia Millia Islamia, New Delhi, India
2 School of Engineering Sciences and Technology, Jamia Hamdard, New Delhi, India

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Date of Submission29-Jan-2020
Date of Acceptance13-May-2020
Date of Web Publication15-Oct-2020


Purpose: 3D Holography is a commercially available, disruptive innovation, which can be customised as per the requirements and is supporting Industry 4.0. The purpose of this paper is to study the potential applications of 3D holography in the medical field. This paper explores the concept of holography and its significant benefits in the medical field.
Methods: The paper is derived through the study of various research papers on Holography and its applications in the medical field. The study tries to identify the direction of research &development and see how this innovative technology can be used effectively for better treatment of patients.
Results: Holography uses digital imaging inputs and provides an extensive visualisation of the data for training doctors, surgeons and students. Holography converts information about the body into a digital format and has the potential to inform, promote and entertain the medical students and doctors. However, it needs a large amount of space for data storage and extensive software support for analysis and skills for customising. This technology seems good to solve a variety of medical issues by storing and using patient data in developing 3D holograms, which are useful to assist successful treatment and surgery. It seems useful in providing flexible solutions in the area of medical research. Finally, the paper identifies 13 significant applications of this technology in the medical field and discusses them appropriately.
Conclusion: The paper explores holographic applications in medical research due to its extensive capability of image processing. Holographic images are non-contact 3D images having a large field of depth. A physician can now zoom the holographic image for a better view of the medical part. This innovative technology can create advancements in the diagnosis and treatment process, which can improve medical practice. It helps in quick detection of problems in various organs like brain, heart, liver, kidney etc. By using this technology, medical practitioners can see colourful organs at multiple angles with better accuracy. It opens up an innovative way of planning, testing of procedures and diagnosis. With technological developments, compact hardware and software are now available to help medical research and related applications.

Keywords: 3D image; applications; detection of disease; holography; imaging; planning; treatment

How to cite this article:
Haleem A, Javaid M, Khan IH. Holography applications toward medical field: An overview. Indian J Radiol Imaging 2020;30:354-61

How to cite this URL:
Haleem A, Javaid M, Khan IH. Holography applications toward medical field: An overview. Indian J Radiol Imaging [serial online] 2020 [cited 2021 Feb 24];30:354-61. Available from:

   Introduction Top

Holography is an innovative technology that depicts an effective interaction of humans with the digital world. It is a disruptive innovation; where 3D imaging technologies are used effectively to address challenges in education, training, research, gaming and other associated areas. In the medical field, it can be used for surgical planning, medical diagnostics, radiology and also for obtaining better information about tissues and organs (internal and external) when viewed from various angles. It can record high-resolution images of tissues and internal organs. Holography seems to be a good tool to plan an intervention as it opens a new possibility due to its capability of non contact high-resolution imaging and measurement. It provides better information about cavities and deformities in internal organs. It helps physicians during the procedure for the fitting of implants.[1],[2]

In few industries, holography is used to protect against duplication of the product as it has an excellent capability for the inspection of the product. This technology is available to capture information about vehicles and their number plates. The other applications are in movies, video games etc. Holography is well used for the retail, military and other commercial applications. It assists specific instruction of the patient and eliminates checkup manually. Holography is used for the detailed study of different parts of ear; such as outer ear, middle ear and inner ear under various noisy conditions. It is used for various applications like cornea, tympanic membrane, tooth mobility, basilar membrane, temporal bone, cochlea, incudomalleal joint, skull, chest and bones.[3],[4]

In cardiology, it is suitable for the therapy of arrhythmias, coronary interventions and heart valve replacements. It provides fast growth to improve healthcare infrastructure[5],[6],[7] and endless possibilities in emergency medical care.[8],[9]

   3d Holography and Its Basic Steps Top

In 1948, this technology was coined by Dr Dennis Gabor for which he received the Nobel Prize. The word hologram stands for 'complete message' which means the reconstruction of the image to convey complete message/information of the given part. Hologram refers to an image that is created when the light reflects upon meeting an object. Thus, it can be seen or obtained with the help of dense air like mist. A hologram is a permanent record of light, which is encapsulated in a three-dimensional object like glass or mirror. Hologram consist of two beams; a reference and an object beam which are diverted with the help of a half mirror and then the light converges forming a hologram using two full mirrors. This technique is used to perform imaging of multidimensional objects. Holography uses hardware, software and more exotic types of programming to create hologram image. This technology records light scattered from an object to present it in a 3D digital image. It allows light to shine through and the image is viewed from one side. The scattering of a laser beam produces multiple light waves that illuminate an object and create an image due to the principle of diffraction. It is recorded through a video camera in a 3D format. A hologram is a 3D photographic technique which projects image using 3D glasses.[1] Hologram diffracts light into an image and is easily projected for planning, teaching, learning and performing of complex surgeries. [Figure 1] shows the fundamental physics of 3D holography.
Figure 1: Basic physics of 3D holography

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A laser is used to focus the light beam and this beam is further spat. By the spat of the laser beam, an object beam is developed which focusses on the mirror. This action finally provides a hologram of the object. This hologram can also be an image of a patient's body part which can be used successfully in the medical field. The applications of this technology are also increasing in the movie industry.

Steps for using holography in the medical field

Holography provides better communication for humans due to the extensive capability of 3D visualisation of a patient's body with high resolution. It is used to simplify the procedure of complex treatments. 3D hologram created by this technology is used for clinical applications by the health professionals. [Figure 2] shows the major steps for developing 3D holograms for clinical applications in the medical field.
Figure 2: Steps used by holography in the medical field

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The first step is to install the required hardware and software for the preparation of the required medical image. This prepared image is then projected, by which one can see, a 3D hologram. This hologram is visualised by the doctors and surgeons for proper planning of the treatment which is applied for clinical applications and provides various benefits in the medical field.

   Need for the Study Top

Holography is an innovative imaging technology which creates detailed imaging that can be used for different applications. In medical imaging, there is a requirement of imaging of internal and external human body parts. There are digital imaging technologies which provide 2dimensional and even 3D images of body parts. Thus, we need to go a step further to see these images in motions, with different scales, with different colours and with languages. Its applications are increasing in image processing and precisely measuring human body parts.

Literature gives us a good idea of the applications of holography used to measure the stress on surgical tools during surgery. It allows examining the different body parts like liver, brain, skeleton, heart, lungs, nerves, vascular system and muscles. It can digitally store patient data and provide a massive amount of detailed information.[10],[11] Thus, it is suitable for medical training, tumor localisation and remote therapy, visualisation and complex 3D structure measurement of the human body. In the medical field, holography is used to measure the natural cavity, organs and tissue of the human body in a non-destructive manner. This 3D visualising technology provides a unique experience to the doctor and offers empowerment to clinicians. It efficiently performs the studies of bones in a contactless manner.[12],[13]

The need is to understand holography, its basic functioning and identify its significant benefits in using it in the field of medicine. Further, we need to understand the benefits it can deliver to the practitioners. This will help readers to be aware of what is now technologically feasible and may help in changing the perception about the latest developments. Secondly, this will help researchers and doctors in developing future applications.

   Benefits of Holography Top

This technology is rapidly growing in the medical field for its use in practical studies and explanation. The enormous potential of holography is to import and use high-capacity data. It stores information about multiple images at different angles.[1],[12] Different benefits of holography in the medical field are as under:

  • Improve the way of procedure and treatment
  • Provide advanced imaging
  • Effective learning
  • Useful for multiple images
  • Capacity of storing
  • Do not require any projection screen
  • Save cost in processes
  • Improve customer care
  • Increase the efficiency of doctors and surgeons
  • 3D visualisation of products and situations
  • Do not require special glasses to view
  • Store preserve and archive information

Thus, holography provides advancements in education, planning, security, safety and research and development.

   Holography for Radiologists Top

Holography is an advanced imaging technique that helps radiologists to identify injury or any other fracture in the soft or hard tissue of patients. It improves the safety and better treatment of the patients. With the help of this innovative imaging technique, all previous medical records of the patient can be stored digitally, by which a radiologist can easily examine the medical history of a patient. It has several applications in radiology like cardiovascular, chest, genitourinary, musculoskeletal, neuroradiology, paediatric and head and neck radiology. Holography has excellent capabilities for radiology towards using truly virtual 3D images. It provides a more information to radiologists as compared to 2D images and maintains a vast amount of information due to its electronic storage capability. This technology is useful in radiology for the planning of different surgical approaches by guiding invasive procedures.[2],[13] It stores and retrieves 3D information which was a big challenge for traditional imaging technologies.

   Some Cases on Holography in the Medical Field Top

Aarnisalo et al., 2009 performed a case to assess the position and thickness of a cartilage by using holography.[5] Salvetti and Bertagni, 2016 used hologram to develop a medical test and devices used to monitor various conditions like infection, cardiac function and diabetes. This is used for advanced medical simulation and enables face-to-face training. It rapidly emerging in healthcare and makesthe education process more efficient and effective.[14] Pathania et al., 2016 used holography for the proper assessment of lymphoma tissue. This is an essential technology to identify the cancer accurately in lesser time.[12] Mishra, 2017 used holography for primitive designing in medical science. An organ hologram can be zoomed and edited in 3D space which makes the treatment and diagnosis processes more effective. In future, this technology can prevent uncomfortable physical procedures.[1]

   Holography Applications in the Medical Field Top

Holography facilitates excellence in healthcare by sorting out complications in imaging. This technology can be useful to eliminate the requirements of physical testing procedure.[15],[16] It easily stores digital 3D images of the patient or body parts. It employs reliable and efficient management of all records, and with better devices and improved storage facility, it is easy to analyse the progress.[17],[18] Holograms are available for various medical test and devices and are used to monitor diabetes, infections and check the proper functioning of soft and hard tissues. This technology is available to check drug, hormones, alcohol and glucose.[19],[20]

Doctors can now use Colourful holography for proper monitoring and clinical trials and for studying complex images vascular, nervous and musculoskeletal systems. Now, doctors and surgeon can see the detailed images of soft and hard tissue of the human body. They can also see the human body from outside. Holography has the potential for a high level of achievement in medical research and development. [Table 1] gives significant applications of holography in the medical field.
Table 1: Major applications of holography in the medical field

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By using a holographic image, doctors can improve the quality of medical education and research. It used to reconstruct the image of tissue samples which helps to perform tissue surgeries. This technology is used for making the digital 3D prototype for neuroscience. This also offers help in the study of different orthopaedics structure. It is applicable to measure the strain on rods, pins and different bone fracture. Doctors can now see the anatomy of the patient without cutting into the body.[14],[65] It is useful to create technological advancement in the medical field.

   Discussion Top

In the healthcare industry, the demand for medical holography is increasing for new treatment. The massive ability of this technology is to record and read data. Doctors and surgeon can enhance their communication with the patient to address the complex medical problem. It creates moving 3D images of body parts to create advancement in the imaging field. It helps doctors for proper diagnosis and treatment in a secure and timely manner. The applications of this technology are for medical imaging, urology, orthopaedics and medical institutions for research and development process. Medical images are visualised to create a hyper-realistic experience to empower the clinician. It helps measurements of internal cavities of the human body non-destructively. In dentistry, it is used to store tooth prints digitally. It quickly tests breath, saliva, blood and urine and provides a better understanding as compared to books/images. This technology provides a virtual environment, which helps to solve a complex issue.

However, it needs a large amount of storage space for better treatment of disease and injury. In orthopaedics, holography is an emerging tool to study and measure the external fracture of the bone. It allows seeing the structure of bone and their movement in real-time. These images help doctors for the treatment without the presence of the patient. Holography completely disrupts the way of communication of medical professionals. It avoids misunderstanding of a specific medical problem ensuring a better treatment. This digital holography is used to perform effective diagnosis and provide more clarity and patient satisfaction.

   Limitations and Future Scope Top

It requires highly skilled human resources for capturing the 3D image. Most of the people are unfamiliar with this technology. Expensive hardware and software are required to produce and view the medical images. Holography imaging is costly as compared to 2D imaging. This technology is not successful during complex movements. The images captured by this technology are time-consuming and need specialised hardware and software. Export of datasets to create a hologram is a big concern.

In future, holography will provide 'Holodoctors' in the medical industry. It is possible that a doctor in a remote location can see the holography image and provide treatment. It will also be helpful for the manufacturing of pharmaceutical and healthcare products. In future, holography will provide an innovative solution for the development of healthcare. These 3D holographic images will also be helpful for business purposes. There is a need for medical persons to develop better applications of holography in their respective areas.

   Conclusion Top

Holography has emerged as an innovative technology to record and display information in 3D format. The applications of this technology are in different fields of medical, engineering, science, graphics and arts. It plays a vital role in personalised medicine and healthcare facilitation. Holography image lowers the cost of planning and provides better outcomes for the patient. This technology is helpful for remote places in which the hologram of a patient is sent to the doctors by emails which can be examine for the status of the diseases without the physical presence of the patient. It is used for better planning of interventional procedures of structural heart diseases. A physician can manipulate a 3D heart structure in a holographic image. Thus, it can be used for better understanding of a patient's heart during the procedure.

Holography has good applications in ophthalmology, audiology, orthopaedics and dentistry. In medical science, holography is growing faster towards improving the understanding and better communications by which doctors can see the detailed structure of the patient. It provides a better understanding of multiple organs, anatomical structures and blood vessels. This technology is useful to develop 3D hologram of various cells, organs and tissue, which can further be studied from various angles. It is helpful to research and study the effects of various drugs on the individual patient. It improves the understanding of the complex anatomy of the individual patient and can also provide better information regarding chronic kidney disease. This technology seems to be a better teaching tool as compared to other conventional imaging tools.

Financial support and sponsorship


Conflicts of interest

There are no conflicts of interest.

   References Top

Mishra S. Hologram the future of medicine - From Star Wars to clinical imaging. Indian Heart J2017;69:566-7.  Back to cited text no. 1
Haleem A, Javaid M, Vaishya R. Holography applications for orthopaedics. Indian J Radiol Imaging 2019;29:477-9.  Back to cited text no. 2
[PUBMED]  [Full text]  
Kreider W, Yuldashev PV, Sapozhnikov OA, Farr N, Partanen A, Bailey MR, et al. Characterization of a multi-element clinical HIFU system using acoustic holography and nonlinear modeling. IEEE Trans Ultrason Ferroelectr Freq Control 2013;60:1683-98.  Back to cited text no. 3
Khaleghi M, Guignard J, Furlong C, Rosowski JJ. Simultaneous full-field 3-D vibrometry of the human eardrum using spatial-bandwidth multiplexed holography. J Biomed Opt 2015;20:111202. doi: 10.1117/1.JBO.20.11.111202.  Back to cited text no. 4
Aarnisalo AA, Cheng JT, Ravicz ME, Hulli N, Harrington EJ, Hernandez-Montes MS, et al. Middle ear mechanics of cartilage tympanoplasty evaluated by laser holography and vibrometry. Otol Neurotol 2009;30:1209-14.  Back to cited text no. 5
Mudanyali O, Tseng D, Oh C, Isikman SO, Sencan I, Bishara W, et al. Compact, light-weight and cost-effective microscope based on lensless incoherent holography for telemedicine applications. Lab Chip 2010;10:1417-28.  Back to cited text no. 6
Haleem A, Javaid M, Vaishya, R. Industry 4.0 and its applications in orthopaedics. J Clin Orthop Trauma 2019:10:615-6.  Back to cited text no. 7
Wei Q, McLeod E, Qi H, Wan Z, Sun R, Ozcan A. On-chip cytometry using plasmonic nanoparticle enhanced lens-free holography. Sci Rep 2013;3:1699. doi: 10.1038/srep01699.  Back to cited text no. 8
Khaleghi M, Furlong C, Ravicz M, Cheng JT, Rosowski JJ. Three-dimensional vibrometry of the human eardrum with stroboscopic lensless digital holography. J Biomed Opt 2015;20:051028. doi: 10.1117/1.JBO.20.5.051028.  Back to cited text no. 9
Wang Y, Yang Y, Wang D, Ouyang L, Zhang Y, Zhao J, et al. Morphological measurement of living cells in methanol with digital holographic microscopy. Comput Math Methods Med 2013;2013:715843. doi: 10.1155/2013/715843.  Back to cited text no. 10
Liu CH, Schill A, Raghunathan R, Wu C, Singh M, Han Z, et al. Ultra-fast line-field low coherence holographic elastography using spatial phase shifting. Biomed Opt Express 2017;8:993-1004.  Back to cited text no. 11
Pathania D, Im H, Kilcoyne A, Sohani AR, Fexon L, Pivovarov M, et al. Holographic assessment of lymphoma tissue (HALT) for global oncology field applications. Theranostics 2016;6:1603-10.  Back to cited text no. 12
Bernhardt M, Nicolas JD, Osterhoff M, Mittelstädt H, Reuss M, Harke B, et al. Correlative microscopy approach for biology using X-ray holography, X-ray scanning diffraction and STED microscopy. Nat Commun 2018;9:3641. doi: 10.1038/s41467-018-05885-z.  Back to cited text no. 13
Salvetti F, Bertagni B. Interactive holograms and tutorials in healthcare education: Case studies from the e-REAL experience. Int J Adv Corporate Learn 2016;9. doi: 10.3991/ijac.v9i2.5988.  Back to cited text no. 14
Burgner J, Simpson AL, Fitzpatrick JM, Lathrop RA, Herrell SD, Miga MI, et al. A study on the theoretical and practical accuracy of conoscopic holography-based surface measurements: Toward image registration in minimally invasive surgery. Int J Med Robot 2013;9:190-203.  Back to cited text no. 15
Prozorov T, Almeida TP, Kovács A, Dunin-Borkowski RE. Off-axis electron holography of bacterial cells and magnetic nanoparticles in liquid. J R Soc Interface 2017;14. pii: 20170464. doi: 10.1098/rsif. 2017.0464.  Back to cited text no. 16
Isikman SO, Bishara W, Mudanyali O, Sencan I, Su TW, Tseng D, et al. Lensfree on-chip microscopy and tomography for bio-medical applications. IEEE J Sel Top Quantum Electron 2011;18:1059-72.  Back to cited text no. 17
Lin WT, Lin CY, Singh VR, Luo Y. Speckle illumination holographic non-scanning fluorescence endoscopy. J Biophotonics 2018;11:e201800010. doi: 10.1002/jbio.201800010.  Back to cited text no. 18
Sapozhnikov OA, Tsysar SA, Khokhlova VA, Kreider W. Acoustic holography as a metrological tool for characterizing medical ultrasound sources and fields. J Acoust Soc Am 2015;138:1515-32.  Back to cited text no. 19
Guillon M, Forget BC, Foust AJ, De Sars V, Ritsch-Marte M, Emiliani V. Vortex-free phase profiles for uniform patterning with computer-generated holography. Opt Express 2017;25:12640-52.  Back to cited text no. 20
Stockmar M, Cloetens P, Zanette I, Enders B, Dierolf M, Pfeiffer F, et al. Near-field ptychography: Phase retrieval for inline holography using a structured illumination. Sci Rep 2013;3:1927. doi: 10.1038/srep01927.  Back to cited text no. 21
Zhang J, Sun J, Chen Q, Li J, Zuo C. Adaptive pixel-super-resolved lensfree in-line digital holography for wide-field on-chip microscopy. Sci Rep 2017;7:11777. doi: 10.1038/s41598-017-11715-x.  Back to cited text no. 22
Yamada S, Kakue T, Shimobaba T, Ito T. Interactive holographic display based on finger gestures. Sci Rep 2018;8:2010. doi: 10.1038/s41598-018-20454-6.  Back to cited text no. 23
Wu Y, Luo Y, Chaudhari G, Rivenson Y, Calis A, de Haan K, et al. Bright-field holography: Cross-modality deep learning enables snapshot 3D imaging with bright-field contrast using a single hologram. Light Sci Appl 2019;8:25. doi: 10.1038/s41377-019-0139-9.  Back to cited text no. 24
Simpson AL, Sun K, Pheiffer TS, Rucker DC, Sills AK, Thompson RC, et al. Evaluation of conoscopic holography for estimating tumor resection cavities in model-based image-guided neurosurgery. IEEE Trans Biomed Eng 2014;61:1833-43.  Back to cited text no. 25
Plascencia-Villa G, Ponce A, Collingwood JF, Arellano-Jiménez MJ, Zhu X, Rogers JT, et al. High-resolution analytical imaging and electron holography of magnetite particles in amyloid cores of Alzheimer's disease. Sci Rep 2016;6:24873. doi: 10.1038/srep24873.  Back to cited text no. 26
Rivenson Y, Wu Y, Wang H, Zhang Y, Feizi A, Ozcan A. Sparsity-based multi-height phase recovery in holographic microscopy. Sci Rep 2016;6:37862. doi: 10.1038/srep37862.  Back to cited text no. 27
Moon I, Javidi B. Three-dimensional identification of stem cells by computational holographic imaging. J R Soc Interface 2007;4:305-13.  Back to cited text no. 28
Kjeldsen HD, Kaiser M, Whittington MA. Near-field electromagnetic holography for high-resolution analysis of network interactions in neuronal tissue. J Neurosci Methods 2015;253:1-9.  Back to cited text no. 29
Ronzitti E, Conti R, Zampini V, Tanese D, Foust AJ, Klapoetke N, et al. Submillisecond optogenetic control of neuronal firing with two-photon holographic photoactivation of chronos. J Neurosci 2017;37:10679-89.  Back to cited text no. 30
Nesterets Y, Gureyev T, Stevenson A, Pogany A, Wilkins S, Kincaid R, et al. Soft tissue small avascular tumor imaging with x-ray phase-contrast micro-CT in-line holography. Proc SPIE Int Soc Opt Eng 2008;6913:69133z. doi: 10.1117/12.772761.  Back to cited text no. 31
Dobrev I, Furlong C, Cheng JT, Rosowski JJ. Full-field transient vibrometry of the human tympanic membrane by local phase correlation and high-speed holography. J Biomed Opt 2014;19:96001.  Back to cited text no. 32
Rong L, Latychevskaia T, Chen C, Wang D, Yu Z, Zhou X, et al. Terahertz in-line digital holography of human hepatocellular carcinoma tissue. Sci Rep 2015;5:8445. doi: 10.1038/srep08445.  Back to cited text no. 33
Buzalewicz I, Kujawińska M, Krauze W, Podbielska H. Novel perspectives on the characterization of species-dependent optical signatures of bacterial colonies by digital holography.PLoS One 2016;11:e0150449. doi: 10.1371/journal.pone.0150449.  Back to cited text no. 34
Tahara T, Quan X, Otani R, Takaki Y, Matoba O. Digital holography and its multidimensional imaging applications: A review. Microscopy (Oxf) 2018;67:55-67.  Back to cited text no. 35
Nobukawa T, Katano Y, Muroi T, Kinoshita N, Ishii N. Bimodal incoherent digital holography for both three-dimensional imaging and quasi-infinite-depth-of-field imaging. Sci Rep 2019;9:3363. doi: 10.1038/s41598-019-39728-8.  Back to cited text no. 36
Siegel N, Storrie B, Bruce M, Brooker G. CINCH (confocal incoherent correlation holography) super resolution fluorescence microscopy based upon FINCH (Fresnel incoherent correlation holography). Proc SPIE Int Soc Opt Eng 2015;9336:93360S. doi: 10.1117/12.2081319.  Back to cited text no. 37
Brudfors M, García-Vázquez V, Sesé-Lucio B, Marinetto E, Desco M, Pascau J. ConoSurf: Open-source 3D scanning system based on a conoscopic holography device for acquiring surgical surfaces. Int J Med Robot 2017;13:e1788. doi: 10.1002/rcs.1788.  Back to cited text no. 38
Bedrossian M, Barr C, Lindensmith CA, Nealson K, Nadeau JL. Quantifying microorganisms at low concentrations using digital holographic microscopy (DHM). J Vis Exp 2017;:e56343. doi: 10.3791/56343.  Back to cited text no. 39
Rodríguez GL, Weber J, Sandhu JS, Anastasio MA. Feasibility study of complex wavefield retrieval in off-axis acoustic holography employing an acousto-optic sensor. Ultrasonics 2011;51:847-52.  Back to cited text no. 40
Jo Y, Park S, Jung J, Yoon J, Joo H, Kim MH, et al. Holographic deep learning for rapid optical screening of anthrax spores. Sci Adv 2017;3:e1700606. doi: 10.1126/sciadv.1700606.  Back to cited text no. 41
Krenkel M, Toepperwien M, Alves F, Salditt T. Three-dimensional single-cell imaging with X-ray waveguides in the holographic regime. Acta Crystallogr A Found Adv 2017;73:282-92.  Back to cited text no. 42
Song J, Leon Swisher C, Im H, Jeong S, Pathania D, Iwamoto Y, et al. Sparsity-based pixel super resolution for lens-free digital in-line holography. Sci Rep 2016;6:24681. doi: 10.1038/srep24681.  Back to cited text no. 43
Bocanegra Evans H, Gorumlu S, Aksak B, Castillo L, Sheng J. Holographic microscopy and microfluidics platform for measuring wall stress and 3D flow over surfaces textured by micro-pillars. Sci Rep 2016;6:28753. doi: 10.1038/srep28753.  Back to cited text no. 44
Merola F, Memmolo P, Miccio L, Savoia R, Mugnano M, Fontana A, et al. Tomographic flow cytometry by digital holography. Light Sci Appl 2017;6:e16241. doi: 10.1038/lsa.2016.241.  Back to cited text no. 45
Furlong C, Dobrev I, Rosowski J, Cheng J. Assessing eardrum deformation by digital holography. SPIE Newsroom 2013. doi: 10.1117/2.1201212.004612.  Back to cited text no. 46
Merrill D, An R, Turek J, Nolte DD. Digital holography of intracellular dynamics to probe tissue physiology. Appl Opt 2015;54:89-97.  Back to cited text no. 47
Haleem A, Javaid M. Additive manufacturing applications in Industry 4.0: A review. J Indus Integration Manag 2019. doi: 10.1142/S2424862219300011.  Back to cited text no. 48
Aarnisalo AA, Cheng JT, Ravicz ME, Furlong C, Merchant SN, Rosowski JJ. Motion of the tympanic membrane after cartilage tympanoplasty determined by stroboscopic holography. Hear Res 2010;263:78-84.  Back to cited text no. 49
Bishara W, Sikora U, Mudanyali O, Su TW, Yaglidere O, Luckhart S, et al. Holographic pixel super-resolution in portable lensless on-chip microscopy using a fibre-optic array. Lab Chip 2011;11:1276-9.  Back to cited text no. 50
De Angelis A, Ferrara MA, Coppola G, Di Matteo L, Siani L, Dale B, et al. Combined Raman and polarization sensitive holographic imaging for a multimodal label-free assessment of human sperm function. Sci Rep 2019;9:4823. doi: 10.1038/s41598-019-41400-0.  Back to cited text no. 51
Galeotti JM, Siegel M, Stetten G. Real-time tomographic holography for augmented reality. Opt Lett 2010;35:2352-4.  Back to cited text no. 52
Makey G, Yavuz Ö, Kesim DK, Turnalı A, Elahi P, Ilday S, et al. Breaking crosstalk limits to dynamic holography using orthogonality of high-dimensional random vectors. Nat Photonics 2019;13:251-6.  Back to cited text no. 53
Javaid M, Haleem, A. Industry 4.0 applications in medical field: A brief review. Curr Med Res Pract 2019;9:102-9.  Back to cited text no. 54
Rosen J, Indebetouw G, Brooker G. Homodyne scanning holography. Opt Express 2006;14:4280-5.  Back to cited text no. 55
Flores-Moreno JM, Furlong C, Rosowski JJ, Harrington E, Cheng JT, Scarpino C, et al. Holographic otoscope for nano displacement measurements of surfaces under dynamic excitation. Scanning 2011;33:342-52.  Back to cited text no. 56
Cheng JT, Aarnisalo AA, Harrington E, Hernandez-Montes Model S, Furlong C, Merchant SN, et al. Motion of the surface of the human tympanic membrane measured with stroboscopic holography. Hear Res 2010;263:66-77.  Back to cited text no. 57
Khaleghi M, Lu W, Dobrev I, Cheng JT, Furlong C, Rosowski JJ. Digital holographic measurements of shape and 3D sound-induced displacements of Tympanic Membrane. Opt Eng 2013;52:101916. doi: 10.1117/1.OE.52.10.101916.  Back to cited text no. 58
Sobieranski AC, Inci F, Tekin HC, Yuksekkaya M, Comunello E, Cobra D, et al. Portable lensless wide-field microscopy imaging platform based on digital inline holography and multi-frame pixel super-resolution. Light Sci Appl 2015;4:e346. doi: 10.1038/lsa.2015.119.  Back to cited text no. 59
Shevkunov I, Katkovnik V, Claus D, Pedrini G, Petrov NV, Egiazarian K. Spectral object recognition in hyperspectral holography with complex-domain denoising. Sensors (Basel) 2019;19:5188. doi: 10.3390/s19235188.  Back to cited text no. 60
Haleem A, Javaid M, Khan IH. Current status and applications of Artificial Intelligence (AI) in medical field: An overview. Curr Med Res Pract 2020;9:231-7.  Back to cited text no. 61
Cantu-Valle J, Ruiz-Zepeda F, Mendoza-Santoyo F, Jose-Yacaman M, Ponce A. Calibration for medium resolution off-axis electron holography using a flexible dual-lens imaging system in a JEOL ARM 200F microscope. Ultramicroscopy 2014;147:44-50. doi: 10.1016/j.ultramic.2014.06.003. Epub 2014 Jun 30. PMID: 25016585; PMCID: PMC4307790.  Back to cited text no. 62
Haleem A, Javaid M, Khan MI. Artificial intelligence (AI) applications in dentistry. Curr Med Res Pract 2019. doi: 10.1016/j.cmrp.2019.12.002.  Back to cited text no. 63
Ozsoy-Keskinbora C, Boothroyd CB, Dunin-Borkowski RE, van Aken PA, Koch CT. Hybridization approach to in-line and off-axis (electron) holography for superior resolution and phase sensitivity. Sci Rep 2014;4:7020. doi: 10.1038/srep07020. PMID: 25387480; PMCID: PMC4228327.  Back to cited text no. 64
Ryu D, Wang Z, He K, Zheng G, Horstmeyer R, Cossairt O. Subsampled phase retrieval for temporal resolution enhancement in lensless on-chip holographic video. Biomed Opt Express 2017;8:1981-95.  Back to cited text no. 65

Correspondence Address:
Dr. Mohd Javaid
Department of Mechanical Engineering, Jamia Millia Islamia, New Delhi - 110 025
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Source of Support: None, Conflict of Interest: None

DOI: 10.4103/ijri.IJRI_39_20

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