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| CASE REPORT |
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| Year : 2020 |
Volume
: 30 | Issue : 2 | Page
: 214-217 |
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A unique presentation of 5-fluorouracil (5-FU) induced cerebral encephalopathy
Shailendra S Naik1, Ilavarasi Vanidassane2, Ekta Dhamija1, Atul Sharma2
1 Department of Radiodiagnosis, IRCH, AIIMS, New Delhi, India
2 Department of Medical Oncology, IRCH, AIIMS, New Delhi, India
Correspondence Address:
Dr. Atul Sharma
Department of Medical Oncology, IRCH, AIIMS, New Delhi - 110 029
India
 Source of Support: None, Conflict of Interest: None  | Check |
DOI: 10.4103/ijri.IJRI_17_19
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5-Fluorouracil (5-FU), a commonly used antimetabolite and antineoplastic agent, has been approved for the treatment of various cancers. It is associated with systemic side-effects such as gastrointestinal problems, neutropenia. 5-FU-related encephalopathy is very rarely reported. Imaging with computed tomography (CT) and magnetic resonance imaging (MRI) plays a key role in diagnosing and monitoring the changes. Since the prognosis of cerebral involvement is usually good if recognized and treated in time, the reporting radiologist and treating physician should be familiar with them. We present a rare case of 5-FU-induced encephalopathy that was diagnosed based on her clinical and MRI findings and managed successfully.
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