Indian Journal of Radiology Indian Journal of Radiology  

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Year : 2015  |  Volume : 25  |  Issue : 3  |  Page : 284-287
A rare case of extra nodal Rosai-Dorfman disease with isolated multifocal osseous manifestation

Department of Radiology, Musculoskeletal and Body MRI Division, University of Arkansas for Medical Sciences, Arkansas, USA

Correspondence Address:
Dr. Maharshi H Patel
Slot 556, 4301 W Markham Street, Little Rock - 72205, Arkansas
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Source of Support: None, Conflict of Interest: None

DOI: 10.4103/0971-3026.161459

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Sinus histiocytosis with massive lymphadenopathy (SHML) or Rosai-Dorfman disease is a non-neoplastic condition which typically presents as massive, bilateral cervical lymphadenopathy and can involve multiple extranodal organ systems such as skin, eyes, and upper respiratory tract in about 28% cases. Bone lesions in association with nodal disease are seen in less than 10% cases. Isolated bone involvement as the only manifestation of SHML is extremely rare, with less than 50 cases reported in the literature. We report a very uncommon case of Rosai-Dorfman disease with isolated multifocal osseous involvement as the only presenting feature, involving about 10 different sites with no lymphadenopathy or other organ system involvement.

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