Indian Journal of Radiology Indian Journal of Radiology  

   Login   | Users online: 1876

Home Bookmark this page Print this page Email this page Small font sizeDefault font size Increase font size     


Year : 2012  |  Volume : 22  |  Issue : 1  |  Page : 63-68
Utility of gray-scale ultrasound to differentiate benign from malignant thyroid nodules

1 Department of Radiological Imaging, Institute of Nuclear Medicine and Allied Sciences (INMAS), Delhi, India
2 Department of Cytopathology, Institute of Nuclear Medicine and Allied Sciences (INMAS), Delhi, India

Correspondence Address:
Manju Bala Popli
Department of Radiological Imaging, Institute of Nuclear Medicine and Allied Sciences (INMAS), Lucknow Road, Delhi - 110 054
Login to access the Email id

Source of Support: None, Conflict of Interest: None

DOI: 10.4103/0971-3026.95407

Rights and Permissions

Objective: The objective was to assess the utility of gray-scale USG to identify patterns of thyroid nodules and to correlate the characteristics of benign and malignant nodules with pathological diagnosis. Materials and Methods: From September 2009 to August 2010, a total of 203 patients (17 males and 186 females), with 240 nodules detected at USG, were included in this study. The characteristics of each nodule were determined. The results were then compared with fine needle aspiration (FNA)/histopathological diagnosis. Results: Of the 240 nodules examined, 44 (18.33%) were found to be malignant on cytopathology. The malignant nodules demonstrated solid or predominantly solid composition (sensitivity 88.6%, specificity 53.5%); presence of microcalcification (sensitivity 65.9%, specificity 97.9%); irregular or poorly defined margins (sensitivity 84%, specificity 88.7%); anteroposterior (AP) diameter > transverse diameter (sensitivity 77.2%, specificity 80.1%); absent or thick incomplete halo (sensitivity 70.4%, specificity 65.8%); and markedly hypoechoic character (sensitivity 65.9%, specificity 84.6%). Among males, malignant nodules were found in 36.8%, whereas in females the occurrence was 16.7%. Conclusion: Gray-scale USG features of thyroid nodules are useful to distinguish patients with clinically significant thyroid nodules from those with innocuous nodules despite the overlap of findings. From our study, it is apparent that the USG findings of poorly defined margins, marked hypoechogenicity, microcalcifications, and a taller-than-wider shape have a high diagnostic accuracy for identifying malignant thyroid nodules.

Print this article     Email this article

 Similar in PUBMED
   Search Pubmed for
   Search in Google Scholar for
 Related articles
  Citation Manager
 Access Statistics
  Reader Comments
  Email Alert *
  Add to My List *
 * Requires registration (Free)

 Article Access Statistics
    PDF Downloaded1409    
    Comments [Add]    
    Cited by others 2    

Recommend this journal