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Year : 2004  |  Volume : 14  |  Issue : 2  |  Page : 153
Peyronie's disease : A case report

Radio Diagnosis, IGMC and Mayo Hospital Nagpur Amarjyoti X-ray and Sonography Clinic, Wardha Road, Dhantoli, Nagpur 440012, India

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Keywords: Penile calcification, Peyronie′s disease

How to cite this article:
Phatak S V, Kolwadkar P K, Phatak M S. Peyronie's disease : A case report. Indian J Radiol Imaging 2004;14:153

How to cite this URL:
Phatak S V, Kolwadkar P K, Phatak M S. Peyronie's disease : A case report. Indian J Radiol Imaging [serial online] 2004 [cited 2021 Feb 25];14:153. Available from:

   Introduction Top

Penile fibromatosis (Peyronie's disease) is characterized by painful erections and curvature of the erect penis, which can be readily detected as a thickened, subcutaneous rubbery or hard plaque usually on the dorsal aspect of distal third of penile shaft. The condition is usually slowly progressive, but spontaneous regression may occur. It is one of the four superficial fibromatosis along the palmer fibromatosis (Dupuytren's contracture), Planter fibromatosis and knuckle pads. Its highest incidence appears to be between 40 and 60 yrs of age [1] its association with systemic sclerosis [2] and Labetalol treatment [3] has been described.

   Case Report Top

A forty two year old man presented with complaints of focal pain associated with penile erection. Radiograph of penis showed linear calcification in penis.

   Discussion Top

Peyronie's disease was first described in 1704. It is named for Franηois de la Peyronie who in 1743 described a patient who had rosary beads of scar tissue to cause upward curvature of penis during erection'. The penile curvature of Peyronie's disease is caused by inelastic scar or plaque that shortens the corpora cavernosa during erection. In approximately one third of patients the scarring involves the dorsal and ventral aspects of shaft such offsetting plaques may cause the penis to be straight but shortened or to have a lateral bend. The circumference of the shaft may also be reduced resulting in an erect penis that is flail at the site of constriction, firm proximal to the constriction and soft distally[4]. Pathologic examination of the thickened plaque shows cellular fibroblastic proliferation surrounded by dense masses of collagen. Calcification and ossification may occur. The process appears to begin as a vasculitis in areolar connective tissue beneath the tunica albugenia[1]. These calcified plaques are seen on Radiographs[5],[6]. Various potential etiologies suspected are penile trauma, its association with conditions with loss of elasticity, flexion of tunica albugenia leading to tear, bleed, clot formation and subsequent fibrin deposition[4]. Treatment of Peyronie's disease is challenging and may include repeated infiltration with steroids, radiotherapy, lithotripsy, plastic surgery and systemic antifibrosis drugs like aminobenzoate potassium[1].

   References Top

1.American osteopathic colleges of dermatology monthly dermatology quiz Feb 2001.(   Back to cited text no. 1    
2.Gualdieri L, Valentini G, Lupoli S, Giordano H Peyronie's disease in Systemic sclerosis report of two cases. J. Rhuumato1 1988 Feb 15 (2): 380-1.  Back to cited text no. 2    
3.Kristensen B O Labetalol induced Peyronie's disease? A case report Acta Med Scand 1979;206(6): 511-2  Back to cited text no. 3    
4.James Fitkin, George T Ho Peyronie's disease current management American family physician August 1999.  Back to cited text no. 4    
5.S. Gamanagatti, Hiralal S. Thulkar Peyronie's disease Ind J Radiol Imag 2003 13:2:155.  Back to cited text no. 5    
6.Ranganayakulu B, Bhaskar GV, Vijay Bhaskar G Ossifying induratio penis plastica (Peyronie's disease) Case report Ind J. of sexually transmitted diseases 1997 July-Dec; 18(2): 85-86.  Back to cited text no. 6    

Correspondence Address:
S V Phatak
Radio Diagnosis, IGMC and Mayo Hospital Nagpur Amarjyoti X-ray and Sonography Clinic, Wardha Road, Dhantoli, Nagpur 440012
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Source of Support: None, Conflict of Interest: None

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This article has been cited by
1 Penile fibromatosis (Peyronieæs disease): A rare disorder
Shehzad, A., Shafiq-ur-Rehman, Shaheen, S., Khan, W.A., Bukhari, M.A., Cheema, S.A.
Journal of Pakistan Association of Dermatologists. 2008; 18(1): 56-59


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