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 Indian J Med Microbiol  
 

Figure 2 (A-F): This is an MRI brain of a term neonate who had been classified as moderate Sarnat clinically. T1W (A-C), T2W (D-F). (A-C) Absent myelination [black arrows] of PLIC, on T1WI (3 + 3). Normal caudate nucleus (0 + 0) [white arrowheads]. Abnormal signal in globus pallidus/putamen (3 + 3) [white arrows], thalamus (1 + 1) (not shown) and cortex (1 + 1) [double black arrows] on T1WI. Abnormal signal in brainstem (1 + 1) [double white arrow], cerebellum (1 + 1) [white stars] and white matter (1 + 1) [black arrowheads] on T1W1. (D-F) On T2WI there is also absence of PLIC myelination (3 + 3) [black arrows]. Normal signal of caudate nucleus (0 + 0). However abnormal signal of globus pallidus/putamen (3 + 3) [white arrows] and thalamus (2 + 2) [black arrowheads] on T2WI. Abnormal signal in cerebellum (1 + 1) [white arrows] and white matter (2 + 2) [black stars] on T2WI. No areas of restricted diffusion on DWI and ADC images (not shown). Therefore, the total score is 44 which is classified as severe HIE. The child, however, had normal developmental outcome at 2 years of age

Figure 2 (A-F): This is an MRI brain of a term neonate who had been classified as moderate Sarnat clinically. T1W (A-C), T2W (D-F). (A-C) Absent myelination [black arrows] of PLIC, on T1WI (3 + 3). Normal caudate nucleus (0 + 0) [white arrowheads]. Abnormal signal in globus pallidus/putamen (3 + 3) [white arrows], thalamus (1 + 1) (not shown) and cortex (1 + 1) [double black arrows] on T1WI. Abnormal signal in brainstem (1 + 1) [double white arrow], cerebellum (1 + 1) [white stars] and white matter (1 + 1) [black arrowheads] on T1W1. (D-F) On T2WI there is also absence of PLIC myelination (3 + 3) [black arrows]. Normal signal of caudate nucleus (0 + 0). However abnormal signal of globus pallidus/putamen (3 + 3) [white arrows] and thalamus (2 + 2) [black arrowheads] on T2WI. Abnormal signal in cerebellum (1 + 1) [white arrows] and white matter (2 + 2) [black stars] on T2WI. No areas of restricted diffusion on DWI and ADC images (not shown). Therefore, the total score is 44 which is classified as severe HIE. The child, however, had normal developmental outcome at 2 years of age