Close
 Indian J Med Microbiol  
 

Figure 7 (A-D): L 2-hydroxyglutaric aciduria – Patient 1: A 4-year-old girl presented with ataxia, nystagmus, dysarthria, slow intellectual decline, and dystonia. (A) Axial T2WI shows hyperintensity in bilateral dentate nuclei and adjacent cerebellar white matter (white arrow). (B) Confluent signal changes in the supratentorial white matter with predominant subcortical involvement (white arrowhead). Bilateral symmetrical signal changes are also noted in the striatum (white arrow). Patient 2: A 9-year-old boy presented with a long-standing history of seizures, extrapyramidal symptoms, and ataxia. (C) Axial T2WI image shows signal changes similar to those of patient 1. (D) A cystic lesion in the right anterior temporal lobe is noted (white arrow). Postcontrast scan (not shown) did not reveal any enhancement. Postoperative histopathological examination showed a low-grade glioma

Figure 7 (A-D): L 2-hydroxyglutaric aciduria – Patient 1: A 4-year-old girl presented with ataxia, nystagmus, dysarthria, slow intellectual decline, and dystonia. (A) Axial T2WI shows hyperintensity in bilateral dentate nuclei and adjacent cerebellar white matter <i>(white arrow)</i>. (B) Confluent signal changes in the supratentorial white matter with predominant subcortical involvement <i>(white arrowhead)</i>. Bilateral symmetrical signal changes are also noted in the striatum <i>(white arrow)</i>. Patient 2: A 9-year-old boy presented with a long-standing history of seizures, extrapyramidal symptoms, and ataxia. (C) Axial T2WI image shows signal changes similar to those of patient 1. (D) A cystic lesion in the right anterior temporal lobe is noted <i>(white arrow)</i>. Postcontrast scan (not shown) did not reveal any enhancement. Postoperative histopathological examination showed a low-grade glioma