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 Indian J Med Microbiol  
 

Figure 4 (A-F): Aicardi–Goutier syndrome – A 7-year-old boy presented with microcephaly, early onset feeding difficulties, and developmental delay. Axial CT sections of the brain show coarse calcifications in the dentate and cerebellar white matter (A) (black arrows), basal ganglia (black arrows), and subcortical white matter (black arrowheads) (B). (C and D) Axial T2WI reveals gross cerebellar and cerebral atrophy. There is extensive frontal predominant white matter hyperintensity (white arrows). (E and F) Axial SWI shows punctate calcifications of the dentate and subcortical white matter. CSF showed lymphocytosis and increased IFN-α Serology was negative for TORCH infections

Figure 4 (A-F): Aicardi–Goutier syndrome – A 7-year-old boy presented with microcephaly, early onset feeding difficulties, and developmental delay. Axial CT sections of the brain show coarse calcifications in the dentate and cerebellar white matter (A) <i>(black arrows)</i>, basal ganglia <i>(black arrows)</i>, and subcortical white matter <i>(black arrowheads)</i> (B). (C and D) Axial T2WI reveals gross cerebellar and cerebral atrophy. There is extensive frontal predominant white matter hyperintensity <i>(white arrows)</i>. (E and F) Axial SWI shows punctate calcifications of the dentate and subcortical white matter. CSF showed lymphocytosis and increased IFN-α Serology was negative for TORCH infections