Malignant melanoma of the choroid is the commonest primary intra-ocular tumor in the adults, 85% arising from the choroid and 15% from the ciliary body. We present two cases of intraocular choroidal melanoma with varied manifestations. One in a fifty two year old man and another in a forty-two years old woman presenting with gradual loss of vision in one eye. A bilobed mushroom shaped (figure of eight shape) intraocular lesion was seen to arise from choroid protruding into the vitreous and revealing a "waist " in it's midportion in the right eye of fifty two year old man. B-Scan of right eye in the forty-two years old woman revealed a large intraocular mass with mid level echos and lobulated contours filling nearly the whole posterior segment.

Retinoblastoma is a primary intraocular neoplasm of childhood, presenting with leukocoria.We present a spectrum of three cases. First two cases are of bilateral retinoblastoma and last case is a retinoblastoma of right eye. All cases are confirmed to be retinoblastoma on operation and consequent histopathological study.

Objectives : To evaluate the coronary arteries by CT angiography (CTA) and calcium scoring (CS) with 16-slice MDCT for detection of coronary artery disease (CAD) by plaque detection, plaque characterization as well as quantifying luminal narrowing and to correlate the incidence and severity of CAD in diabetic and nondiabetic subjects. Materials and Methods: One hundred and five patients (76 men, 29 women) aged 26-89 years underwent MDCT angiography with CS. Significant luminal stenosis was defined as a reduction in lumen diameter greater than or equal to 50%. The presence of calcification was determined by using the Agatston method. Incidence and severity of CAD were noted in diabetic (DM) and nondiabetic (nonDM) patients. Results : On comparing the CS in patients with DM and nonDM, there was a marked increase in the CS in diabetic patients. Seventy six per cent of diabetic patients showed calcific plaques whereas only 37% of nonDM patients showed calcific plaques. Conclusion: DM patients show significantly more CS than nonDM patients. Calcific plaques are more common in DM than nonDM patients. Double and triple vessel involvement is more common in DM than the nonDM patients.