Indian Journal of Radiology and Imaging Indian Journal of Radiology and Imaging

INTERVENTIONAL RADIOLOGY
Year
: 2019  |  Volume : 29  |  Issue : 4  |  Page : 397--403

Stem cell therapy in critical limb ischemia: Current scenario and future trends


Arun Sharma1, Mumun Sinha1, Niraj Nirmal Pandey1, SH Chandrashekhara2 
1 Department of Cardiovascular Radiology and Endovascular Interventions, All India Institute of Medical Sciences, New Delhi, India
2 Department of Radiodiagnosis, BRAIRCH, All India Institute of Medical Sciences, New Delhi, India

Correspondence Address:
Dr. Arun Sharma
Department of Cardiovascular Radiology and Endovascular Interventions, All India Institute of Medical Sciences, New Delhi - 110 029
India

Critical limb ischemia (CLI) represents the most severe manifestation of peripheral arterial disease (PAD). It imposes a huge economic burden and is associated with high short-term mortality and adverse cardiovascular outcomes. Prompt recognition and early revascularization, surgical or endovascular, with the aim of improving the inline bloodflow to the ischemic limb, are currently the standard of care. However, this strategy may not always be feasible or effective; hence, evaluation of newer pharmacological or angiogenic therapies for alleviating the symptoms of this alarming condition is of utmost importance. Cell-based therapies have shown promise in smaller studies; however, large-scale studies, demonstrating definite survival benefits, are entailed to ascertain their role in the management of CLI.


How to cite this article:
Sharma A, Sinha M, Pandey NN, Chandrashekhara S H. Stem cell therapy in critical limb ischemia: Current scenario and future trends.Indian J Radiol Imaging 2019;29:397-403


How to cite this URL:
Sharma A, Sinha M, Pandey NN, Chandrashekhara S H. Stem cell therapy in critical limb ischemia: Current scenario and future trends. Indian J Radiol Imaging [serial online] 2019 [cited 2020 Jun 2 ];29:397-403
Available from: http://www.ijri.org/article.asp?issn=0971-3026;year=2019;volume=29;issue=4;spage=397;epage=403;aulast=Sharma;type=0