Indian Journal of Radiology and Imaging Indian Journal of Radiology and Imaging

NEUROIMAGING
Year
: 2016  |  Volume : 26  |  Issue : 3  |  Page : 316--327

Magnetic resonance imaging spectrum of perinatal hypoxic–ischemic brain injury


Binoj Varghese1, Rose Xavier2, VC Manoj2, MK Aneesh1, PS Priya1, Ashok Kumar1, VK Sreenivasan3 
1 Department of Radiology, Jubilee Mission Medical College and Research Institute, Thrissur, Kerala, India
2 Department of Paediatrics, Jubilee Mission Medical College and Research Institute, Thrissur, Kerala, India
3 Department of Paediatrics, Amala Institute of Medical Sciences, Thrissur, Kerala, India

Correspondence Address:
Dr. Binoj Varghese
Department of Radiodiagnosis, Amala Institute of Medical Sciences (AIMS), Thrissur - 680 055, Kerala
India

Perinatal hypoxic–ischemic brain injury results in neonatal hypoxic–ischemic encephalopathy and serious long-term neurodevelopmental sequelae. Magnetic resonance imaging (MRI) of the brain is an ideal and safe imaging modality for suspected hypoxic–ischemic injury. The pattern of injury depends on brain maturity at the time of insult, severity of hypotension, and duration of insult. Time of imaging after the insult influences the imaging findings. Mild to moderate hypoperfusion results in germinal mazatrix hemorrhages and periventricular leukomalacia in preterm neonates and parasagittal watershed territory infarcts in full-term neonates. Severe insult preferentially damages the deep gray matter in both term and preterm infants. However, associated frequent perirolandic injury is seen in term neonates. MRI is useful in establishing the clinical diagnosis, assessing the severity of injury, and thereby prognosticating the outcome. Familiarity with imaging spectrum and insight into factors affecting the injury will enlighten the radiologist to provide an appropriate diagnosis.


How to cite this article:
Varghese B, Xavier R, Manoj V C, Aneesh M K, Priya P S, Kumar A, Sreenivasan V K. Magnetic resonance imaging spectrum of perinatal hypoxic–ischemic brain injury.Indian J Radiol Imaging 2016;26:316-327


How to cite this URL:
Varghese B, Xavier R, Manoj V C, Aneesh M K, Priya P S, Kumar A, Sreenivasan V K. Magnetic resonance imaging spectrum of perinatal hypoxic–ischemic brain injury. Indian J Radiol Imaging [serial online] 2016 [cited 2020 Aug 6 ];26:316-327
Available from: http://www.ijri.org/article.asp?issn=0971-3026;year=2016;volume=26;issue=3;spage=316;epage=327;aulast=Varghese;type=0