Indian Journal of Radiology and Imaging Indian Journal of Radiology and Imaging

NEURORADIOLOGY
Year
: 2011  |  Volume : 21  |  Issue : 3  |  Page : 221--224

Diffusion tensor imaging in spinal cord injury


Ravindra B Kamble, Neelam K Venkataramana, Arun L Naik, Shailesh V Rao 
 Department of Radiology and Neurosciences, BGS Global Hospital, Bangalore, Karnataka, India

Correspondence Address:
Ravindra B Kamble
Department of Radiology, BGS Global Hospitals, Uttarahalli Road, Kengeri, Bangalore-560060
India

Background and Purpose: To assess the feasibility of spinal tractography in patients of spinal cord injury vs a control group and to compare fractional anisotropy (FA) values between the groups. Materials and Methods: Diffusion tensor imaging (DTI) was performed in the spinal cord of 29 patients (18 patients and 11 controls). DTI was done in the cervical region if the cord injury was at the dorsal or lumbar region and in the conus region if cord injury was in the cervical or dorsal region. FA was calculated for the patients and the controls and the values were compared. Results: The mean FA value was 0.550±0.09 in the control group and 0.367±0.14 in the patients; this difference was statistically significant (P=0.001). Conclusion: Spinal tractography is a feasible technique to assess the extent of spinal cord injury by FA, which is reduced in patients of spinal cord injury, suggesting possible Wallerian degeneration. In future, this technique may become a useful tool for assessing cord injury patients after stem cell therapy, with improvement in FA values indicating axonal regeneration.


How to cite this article:
Kamble RB, Venkataramana NK, Naik AL, Rao SV. Diffusion tensor imaging in spinal cord injury.Indian J Radiol Imaging 2011;21:221-224


How to cite this URL:
Kamble RB, Venkataramana NK, Naik AL, Rao SV. Diffusion tensor imaging in spinal cord injury. Indian J Radiol Imaging [serial online] 2011 [cited 2020 Feb 26 ];21:221-224
Available from: http://www.ijri.org/article.asp?issn=0971-3026;year=2011;volume=21;issue=3;spage=221;epage=224;aulast=Kamble;type=0