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NEURORADIOLOGY Table of Contents   
Year : 2017  |  Volume : 27  |  Issue : 2  |  Page : 129-132
Sequential MR imaging (with diffusion-weighted imaging) changes in metronidazole-induced encephalopathy


1 Department of Neuroradiology, Sri Bala Ji Action Medical Institute, New Delhi, India
2 Department of Gynaecology, Kasturba Hospital, New Delhi, India
3 Department of Neurology, Sri Bala Ji Action Medical Institute, New Delhi, India

Correspondence Address:
Rupinder Singh
Department of Neuroradiology, Sri Bala Ji Action Medical Institute, New Delhi
India
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Source of Support: None, Conflict of Interest: None


DOI: 10.4103/ijri.IJRI_341_16

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Metronidazole-induced neuro-toxicity, though rare, is known. A characteristic spatial distribution of lesions in cerebellar dentate nuclei and dorsal pons is known. However, temporal progression of lesions on magnetic resonance imaging (MRI) has not been described previously. We describe two such cases which presented initially with splenial hyperintesity and showed progression to characterstic lesions. Both cases improved with stoppage of metronidazole.


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