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NEURORADIOLOGY Table of Contents   
Year : 2013  |  Volume : 23  |  Issue : 3  |  Page : 195-197
MRI brain in monohalomethane toxic encephalopathy: A case report


1 Department of Radiology, Star Imaging and Research Centre, Opp. Kamala Nehru Park, Joshi Hospital Campus, Erandwane, Pune, Maharashtra, India
2 Neurology OPD, Poona Hospital and Research Centre, 27, Sadashiv Peth, Pune, Maharashtra, India

Correspondence Address:
Yogeshwari S Deshmukh
Department of Radiology, Star Imaging and Research Centre, Opp. Kamala Nehru Park, Joshi Hospital Campus, Erandwane, Pune - 411 004, Maharashtra
India
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Source of Support: None, Conflict of Interest: None


DOI: 10.4103/0971-3026.120253

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Monohalomethanes are alkylating agents that have been used as methylating agents, laboratory reagents, refrigerants, aerosol propellants, pesticides, fumigants, fire-extinguishing agents, anesthetics, degreasers, blowing agents for plastic foams, and chemical intermediates. Compounds in this group are methyl chloride, methyl bromide, methyl iodide (MI), and methyl fluoride. MI is a colorless volatile liquid used as a methylating agent to manufacture a few pharmaceuticals and is also used as a fumigative insecticide. It is a rare intoxicant. Neurotoxicity is known with both acute and chronic exposure to MI. We present the characteristic magnetic resonance imaging (MRI) brain findings in a patient who developed neuropsychiatric symptoms weeks after occupational exposure to excessive doses of MI.


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