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NEURORADIOLOGY Table of Contents   
Year : 2012  |  Volume : 22  |  Issue : 2  |  Page : 98-105
Pictorial essay: Acute neurological complications in children with acute lymphoblastic leukemia


1 Department of Radiodiagnosis, Tata Memorial Centre, Tata Memorial Hospital, Parel, Mumbai, India
2 Department of Medical Oncology, Tata Memorial Centre, Tata Memorial Hospital, Parel, Mumbai, India

Correspondence Address:
Seema A Kembhavi
Associate Professor, Department of Radiodiagnosis, Tata Memorial Centre, Parel, Mumbai-400012
India
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Source of Support: None, Conflict of Interest: None


DOI: 10.4103/0971-3026.101080

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Acute lymphoblastic leukemia (ALL) is the commonest childhood malignancy with high cure rates due to recent advances in central nervous system (CNS) prophylaxis. The disease per se, as well as the prophylactic therapy, predisposes the child to complications such as cerebrovascular events, infections, drug toxicities, etc. The purpose of this study is to highlight the pathophysiology and the imaging features (with appropriate examples) of these complications and to propose a diagnostic algorithm based on MRI. Interpreting these scans in the light of clinical inputs very often helps the radiologist reach an appropriate diagnosis and help treatment and management.


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