Indian Journal of Radiology Indian Journal of Radiology  

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Year : 2011  |  Volume : 21  |  Issue : 2  |  Page : 155-156
Authors' reply

1 Department of Radiology, BGS Global Hospital, Bangalore, India
2 Department of Plastic Surgery, BGS Global Hospital, Bangalore, India

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Date of Web Publication23-Jun-2011

How to cite this article:
Kamble RB, Shetty RV, Diwakar N, Madhusudan G. Authors' reply. Indian J Radiol Imaging 2011;21:155-6

How to cite this URL:
Kamble RB, Shetty RV, Diwakar N, Madhusudan G. Authors' reply. Indian J Radiol Imaging [serial online] 2011 [cited 2020 Jun 1];21:155-6. Available from:
Dear Sir,

We agree with Parihar et al.[1] that this technique of MRI lymphangiography is relatively noninvasive and useful in depicting lymphatic channels of the lower limb in secondary lymphedema with the added advantages of absence of radiation, multiplanar reconstruction, and precise compartmental localization. [2]

We have used gadopentate dimeglumine (Magnevist, Bayer Schering Pharma, Berlin, Germany) for injection which is different from gadobenate dimeglumine (MultiHance, Bracco, Milano, Italy); Magnevist has low viscosity (2.9 vs 5.3) and low T1 relaxivity (4.1 vs 8.3 at 1.5T) as compared to Multihance. [3],[4] We were not able to demonstrate inguinal lymph nodes probably because Magnevist gets washed away early as it reaches the groin due to low viscosity and low relaxivity. We completely agree with the authors that newer contrast media like Multihance may be a better option to visualize lymphatic channels along with visualization of inguinal lymph nodes in secondary lymphedema due to the higher relaxivity, which may help improve the quality of the technique.

   References Top

1.Parihar A, Suvirya A, Kumar A, Singh R. Interstitial MRI lymphangiography of the lower limbs. Indian J Radiol Imaging 2011;21:00-155.  Back to cited text no. 1
2.Kamble RB, Shetty R, Diwakar N, Madhusudan G. Technical note: MR Lymphangiography of the lower limb in secondary lymphedema. Indian J Radiol Imaging 2011;21:15-7.  Back to cited text no. 2
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3.Runge VM. Safety of magnetic resonance contrast media. Top Magn Reson Imaging 2001;12:309-14.  Back to cited text no. 3
4.Kirchin MA, Runge VM. Contrast agents for magnetic resonance imaging: safety update. Top Magn Reson Imaging 2003;14:426-35.  Back to cited text no. 4

Correspondence Address:
Ravindra B Kamble
Department of Radiology, BGS Global Hospital, Bangalore
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Source of Support: None, Conflict of Interest: None

PMID: 21799601

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