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Year : 2006  |  Volume : 16  |  Issue : 4  |  Page : 997
Bilateral renal cell carcinoma


Dept. of Radiology & Imaging, Sri Venkateswara Institute of Medical Sciences (SVIMS), Tirupati 517 507, India

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How to cite this article:
Lakshmi A Y. Bilateral renal cell carcinoma. Indian J Radiol Imaging 2006;16:997

How to cite this URL:
Lakshmi A Y. Bilateral renal cell carcinoma. Indian J Radiol Imaging [serial online] 2006 [cited 2019 Dec 13];16:997. Available from: http://www.ijri.org/text.asp?2006/16/4/997/32414
Sir,

Bilateral Renal cell carcinoma (RCC) is a rare entity, hence is the interest in this presentation.

A fifty years old female presented with left quadriceps wasting and left L3 radicular pain and a small nodule on the anterior abdominal wall for evaluation. Routine blood work up was normal but for elevated ESR(110mm 1st hour). B.sugar, B.urea and LFT were normal. MRI showed multiple metastases in D10,L1, L2 and 5 vertebral bodies with preserved disc spaces. Work up for the primary revealed evidence of bilateral renal masses in CECT [Figure - 1]. FNAC of right and left renal masses and the nodule on anterior abdominal wall were suggestive of renal cell adenocarcinoma.

RCC accounts for about 3% of adult cancers and constitute about 80-90% of all primary malignant renal tumors. Bilateral RCC is uncommon. It is reported in about 2-4% of the patients of RCC. Bilateral RCC is known to occur in familial and sporadic forms. They may be synchronous or asynchronous in presentation [1]. When the tumor is bilateral, it is an interesting question whether each tumor has a multicentric origin or whether one is a metastasis and the other being the primary. To determine whether bilateral synchronous RCC is the result of contra lateral renal metastasis or independent denovo carcinogenic event, further studies on pathological features and molecular genetics do help [2].

 
   References Top

1.Kume H, Oda H, Nakatsuru Y.Shimitz Y, Takahashi Y, Matsumoto T, Inoue T, Kameyama S, Kitamura T and Ishikawa T.Genetic identification of bilateral Primary or metastatic nonpapillary renal cell carcinoma. BJU international 2000;86:208-212.  Back to cited text no. 1    
2.Blute ML, Itano NB, Cheville JC, Weaver AL, Lohse CM and Zincke H. The effect of bilaterality, pathological features and surgical outcome in nonhereditary renal cell carcinoma. The journal of Urology 2003; 169:1276-1281.  Back to cited text no. 2    

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Correspondence Address:
A Y Lakshmi
Dept. of Radiology & Imaging, Sri Venkateswara Institute of Medical Sciences (SVIMS), Tirupati 517 507
India
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Source of Support: None, Conflict of Interest: None


DOI: 10.4103/0971-3026.32414

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