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Year : 2006  |  Volume : 16  |  Issue : 2  |  Page : 263-265
Radiological quiz - endocrine


From the department of Radiodiagnosis & Imaging, Ruby Hall Clinic, Pune, India

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How to cite this article:
Atre A L, Tandon A, Joshi A, Sangle P. Radiological quiz - endocrine. Indian J Radiol Imaging 2006;16:263-5

How to cite this URL:
Atre A L, Tandon A, Joshi A, Sangle P. Radiological quiz - endocrine. Indian J Radiol Imaging [serial online] 2006 [cited 2019 Nov 22];16:263-5. Available from: http://www.ijri.org/text.asp?2006/16/2/263/29107
A 22years old male presented with features of delayed puberty & incomplete sexual development.On clinical examination there was hypogonadism. Hormonal assays revealed very low concentrations of testosterone, however the levels of follicle-stimulating hormone (FSH) was not raised. MRI was advised to evaluate for clinical suspision of central Pituitary as the cause for this condition. Below are the noncontrast coronal T2 & T1 SPGR MRI images through the region of frontal lobes.


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1.Iovane A, Aumas C, de Roux N: New insights in the genetics of isolated hypogonadotropic hypogonadism. Eur J Endocrinol 2004 Nov; 151 Suppl 3: U83-8[Medline].  Back to cited text no. 1    
2.Merke DP, Tajima T, Baron J, Cutler GB Jr: Hypogonadotropic hypogonadism in a female caused by an X-linked recessive mutation in the DAX1 gene. N Engl J Med 1999; 340(16): 1248-52[Medline].  Back to cited text no. 2    
3.Miura K, Acierno JS, Seminara SB: Characterization of the human nasal embryonic LHRH factor gene, NELF, and a mutation screening among 65 patients with idiopathic hypogonadotropic hypogonadism (IHH). J Hum Genet 2004; 49(5): 265-8[Medline].  Back to cited text no. 3    
4.Seminara SB, Hayes FJ, Crowley WF Jr: Gonadotropin-releasing hormone deficiency in the human (idiopathic hypogonadotropic hypogonadism and Kallmann's syndrome): pathophysiological and genetic considerations. Endocr Rev 1998 Oct; 19(5): 521-39[Medline].  Back to cited text no. 4    
5.Seminara SB, Achermann JC, Genel M, et al: X-linked adrenal hypoplasia congenita: a mutation in DAX1 expands the phenotypic spectrum in males and females. J Clin Endocrinol Metab 1999 Dec; 84(12): 4501-9[Medline].  Back to cited text no. 5    
6.Seminara SB, Messager S, Chatzidaki EE: The GPR54 gene as a regulator of puberty. N Engl J Med 2003 Oct 23; 349(17): 1614-27[Medline].  Back to cited text no. 6    
7.Silveira LF, MacColl GS, Bouloux PM: Hypogonadotropic hypogonadism. Semin Reprod Med 2002 Nov; 20(4): 327-38[Medline].  Back to cited text no. 7    

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Correspondence Address:
A L Atre
Dept of Radiodiagnosis & Imaging, Ruby Hall Clinic, Pune
India
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Source of Support: None, Conflict of Interest: None


DOI: 10.4103/0971-3026.29107

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[Figure - 1], [Figure - 2]



 

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