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Year : 2005  |  Volume : 15  |  Issue : 4  |  Page : 555-556
Radiological quiz - neuroradiology


Department Of Radiodiagnosis, Maulana Azad Medical College And Associated Lok Nayak Hospital, Jawahar Lal Nehru Marg, New Delhi - 110002., India

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How to cite this article:
Singh S, Chowdhury V, Dixit R, Khera G. Radiological quiz - neuroradiology. Indian J Radiol Imaging 2005;15:555-6

How to cite this URL:
Singh S, Chowdhury V, Dixit R, Khera G. Radiological quiz - neuroradiology. Indian J Radiol Imaging [serial online] 2005 [cited 2020 Aug 9];15:555-6. Available from: http://www.ijri.org/text.asp?2005/15/4/555/29172
A boy was born at term to healthy nonconsangineous parents after an uneventful pregnancy. The neonatal period was uneventful. At 12 months of age his developmental milestones delayed and muscle hypotonia appeared. At 16 months, he developed neurodevelopmental regression, generalized symmetrical hypotonia and absent deep tendon reflexes. His weight, height and head circumference were below the third percentile.

Lab investigations revealed elevated blood lactate at rest. Motor nerve conduction velocity test (MNCV) of the peroneal and median nerve was slowed.

An MR examination of the brain on a 1.5 T magnet was performed [Figure - 1],[Figure - 2],[Figure - 3],[Figure - 4]. What is the diagnosis?.


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   References Top

1.DiMauro S, Servidei S, Zeviam M, et al: Cytochrome C oxidase deficiency in Leigh syndrome. Ann Neurol 1987; 22: 498-506.  Back to cited text no. 1    
2.Chi JG, Yoo HW, Chang KH, et al: Leigh subacute necrotizing encephalomyelopathy: Possible diagnosis by CT scan. Neuroradiology 1981;22:141-144.  Back to cited text no. 2    
3.Berkovic SF, Karpati G, Carpenter S, et al: Progressive dystonia with bilateral putaminal hypodensities. Arch Neurol 1987;44 1184-1187.  Back to cited text no. 3    
4.Koch TK, Yee MHC, Hutchinson HT, et al: Magnetic resonance imaging in subacute necrotizing encephalomyelopathy (Leigh disease). Ann Neurol 1986; 19: 605-607, 1986.  Back to cited text no. 4    
5.Leigh D: Subacute necrotizing encephalomyelopathy in an infant. J Neurol Neurosurg Psychiatry 1951; 14: 216-21.  Back to cited text no. 5    

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Correspondence Address:
S Singh
212, Sfs Flats, Phase Iv, Ashok Vihar, Delhi - 110052
India
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Source of Support: None, Conflict of Interest: None


DOI: 10.4103/0971-3026.29172

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    Figures

[Figure - 1], [Figure - 2], [Figure - 3], [Figure - 4]



 

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