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RECENT ADVANCES AND INNOVATION Table of Contents   
Year : 2004  |  Volume : 14  |  Issue : 3  |  Page : 321-328
Molecular imaging : A review- part I (Fundamentals and genetic perspective)


Dept. of Radiology and Imaging, LTM General hospital, Sion, Mumbai-400022, India

Correspondence Address:
S Merchant
Dept. of Radiology and Imaging, LTM General hospital, Sion, Mumbai-400022
India
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Source of Support: None, Conflict of Interest: None


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Molecular imaging is a promising field, which aims at developing and testing various tools, reagents and methods to image specific molecular pathways in humans, particularly those that are key targets in disease processes. Unlike 'classical' diagnostic imaging; instead of the symptoms-oriented search that operates empirically to modify the behavior of the patient, molecular medicine sets forth to probe molecular abnormalities that are the basis of the disease, rather than to image the end effects of these molecular alterations. Radiologists will play a leading role in directing developments of this embryonic but rapidly expanding field. This article presents some basics in molecular sciences and the fundamentals of molecular imaging including itsgenetic perspective and shows how imaging can be used, to assess specific molecular targets. In the future, specific imaging of such targets will allow earlier detection and characterization of disease, earlier and direct molecular assessment of treatment effects, and a more fundamental understanding of the disease processes.


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