Indian Journal of Radiology Indian Journal of Radiology  

   Login   | Users online: 3443

Home Bookmark this page Print this page Email this page Small font sizeDefault font size Increase font size     

 

VASCULAR Table of Contents   
Year : 2003  |  Volume : 13  |  Issue : 1  |  Page : 61-66
Aortoarteritis : A study of 33 central Indian patients


Dept. of Radiodiagnosis, Govt. Medical College, Nagpur-440003, India

Correspondence Address:
R G Salkar
Dept. of Radiodiagnosis, Govt. Medical College, Nagpur-440003
India
Login to access the Email id

Source of Support: None, Conflict of Interest: None


Rights and PermissionsRights and Permissions

OBJECTIVE : To evaluate the clinical profile, complications, site of involvement and response to therapy and interventional management of aortoarteritis. MATERIAL AND METHODS : 33 patients with Aortoarteritis were studied over a period of two years between Jan 2001 to Nov 2002. Data on clinical features, laboratory and angiographic findings, disease course, response to therapy and interventional management were all recorded and stored in a computer based retrieval system. RESULTS : In our series of 33 patients (21 female, 12 male) with angiographically diagnosed Aortoarteritis, females (63.64 percent) were most frequently affected. The median age of onset was 29 years. The clinical presentation ranged from asymptomatic to catastrophic with stroke. Patients had both non-vascular symptoms (fever 21.21 percent, arthralgia 9 percent) and symptom of vascular stenosis such as limb claudication (66.67 percent), headache (66.67 percent), and hypertension due to renal artery Stenosis (42 percent). All patients had either multiple vascular bruits (76 percent), absent pulses (18 percent), or asymmetric pulses (66.67 percent) and blood pressure differences greater than 10 mm hg between arm (66.67 percent). Laboratory findings included elevated erythrocyte sedimentation rate (87.88 percent), C-reactive protein (30.30 percent), one patient had Mantax test positive. However, E.S.R. was not a consistently reliable surrogate marker of the disease activity. Almost all patients had multiple sites of arterial involvement documented by angiogram with various combinations of stenosis, Luminal irregularity and aneurysm formation. Type IV (63.64 percent) (i.e. involvement of abdominal aorta and or renal arteries) was more commonly found in our study. Response to corticosteroid treatment was usually very good, with dramatic improvement in non-vascular symptoms. SIX patients underwent percutaneous transluminal angioplasty involving the abdominal aorta (2 cases), subclavian artery (3cases) and renal artery (lease). CONCLUSIONS : In central India, Aortoarteritis is a rare disease. However, Type IV is more common. It is heterogeneous in presentation, progression, and response to therapy. Current laboratory markers of disease activity are insufficiently reliable to guide management. Most patients require repeated and at times, prolonged course of therapy. After percutaneous transluminal, balloon angioplasty (P.T.A.) clinical parameters were normal. Although mortality was low, substantial morbidity occurred in most patients.


[FULL TEXT] [PDF Not available]*
Print this article     Email this article

 Similar in PUBMED
   Search Pubmed for
   Search in Google Scholar for
 Related articles
  Citation Manager
 Access Statistics
  Reader Comments
  Email Alert *
  Add to My List *
 * Requires registration (Free)
 

 Article Access Statistics
    Viewed10141    
    Printed284    
    Emailed11    
    PDF Downloaded0    
    Comments [Add]    
    Cited by others 1    

Recommend this journal