Indian Journal of Radiology Indian Journal of Radiology  

   Login   | Users online: 1544

Home Bookmark this page Print this page Email this page Small font sizeDefault font size Increase font size     

 

RECENT ADVANCES AND INNOVATION Table of Contents   
Year : 2002  |  Volume : 12  |  Issue : 2  |  Page : 281-284
Multiple and single fraction palliative radiotherapy in bone secondaries a prospective study


Department of Radiotherapy, Medical College, 88, College Street, Calcutta-700073, West Bengal, India

Correspondence Address:
S K Sarkar
80/IE, Kanukilia Road, Calcutta-700029, West Bengal
India
Login to access the Email id

Source of Support: None, Conflict of Interest: None


Rights and PermissionsRights and Permissions

Objective: This prospective study was done to compare the role of the multi fraction (MF) and single fraction (SF) radiotherapy in the management of bone secondaries as regards potency for pain relief and resultant early toxicities. Materials and Methods: Seventy three out of eight five patients with bone metastases, who fulfilled the inclusion criteria were randomly divided into two groups to be treated by External radiation either by 3000 cGy over 2 weeks in 10 Fractions i.e. multiple fraction (MF) or by 8000 cGy in single fraction (SF). Pre and Post radiation pain relief potential and early toxicities due to the treatment were compared. Results: No significant difference (P>0.50) was observed as regards pain relief which was 84% in Gr-I (MF) and 76% in Gr - II (SF). Similarly incidence of complete pain relief, (42% VS - 35%) no response (16% VS 24%) and early toxicities also show marginal difference. Conclusion: Though both the radiation schedules resulted in considerable reduction of Bone pain in majority of the patients, no significant difference was observed as regards pain relief and early toxicities.


[FULL TEXT] [PDF Not available]*
Print this article     Email this article

 Similar in PUBMED
   Search Pubmed for
   Search in Google Scholar for
 Related articles
  Citation Manager
 Access Statistics
  Reader Comments
  Email Alert *
  Add to My List *
 * Requires registration (Free)
 

 Article Access Statistics
    Viewed5325    
    Printed214    
    Emailed6    
    PDF Downloaded0    
    Comments [Add]    
    Cited by others 8    

Recommend this journal