Indian Journal of Radiology Indian Journal of Radiology  

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G I RADIOLOGY Table of Contents   
Year : 1999  |  Volume : 9  |  Issue : 4  |  Page : 159-163
Role of ultrasound-guided percutaneous fine needle aspiration cytology in carcinoma of pancreas


Department of Gastroenterology, Sher-i-Kashmir Institute of Medical Sciences, Srinagar, India

Correspondence Address:
Gul Javid
Department of Gastroenterology,Gilistan Manzil, Amira Kadal-190001, Srinagar
India
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Objective: The present study was undertaken to determine the safety, accuracy and clinical utility of ultrasound guided fine needle aspiration biopsy in the diagnosis of pancreatic masses. Material and methods: Seventy-five patients with clinical and ultrasound suspicion of pancreatic carcinoma were aspirated using a twenty-two gauge, Teflon coated needle under ultrasound guidance. The masses ranged in size from 2.5 to 4.5 cm. Results: This technique confirmed malignancy in 61 of the 70 cases of malignancy (87.1%). Thirty-nine patients including 14 patients with negative aspiration underwent surgery and out of the 14 aspiration­negative patients, five patients had chronic pancreatitis and nine patients had carcinoma. This was confirmed on histology of the biopsy specimen taken at laparotomy. Four patients developed mild abdominal pain after aspiration; one patient developed acute pancreatitis and recovered with conservative treatment. One patient developed peritonitis after aspiration, had extensive tumor of pancreas involving the duodenum and expired later on, after laparotomy. Conclusion: Ultrasound guided fine needle aspiration biopsy of pancreas is a safe, reliable and accurate technique for the diagnosis of malignancy. It has a high diagnostic accuracy of 88%, sensitivity of 73% and a specificity of 100%. The predictive value of positive and negative results, is 100% and 35.71% respectively with a mortality of 1.3%.


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